Journal publications


Allu, S. R.; Ravotto, L.; Troxler, T.; Vinogradov, S. A.syn-Diarylphthalimidoporphyrins: Effects of symmetry breaking on two-photon absorption and linear photophysical properties J. Phys. Chem. A, 2021, 125(14), 2977-2988.

Cao, X.; Allu, S. R.; Jiang, S. D.; Gunn, J. R.; Yao, C. P.; Xin, J.; Bruza, P.; Gladstone, D. J.; Jarvis, L. A.; Tian, J.; Swartz, H. M.; Vinogradov, S. A.; Pogue, B. W. High-resolution pO2 imaging improves quantification of the hypoxic fraction in tumors during radiation therapy International Journal of Radiation Oncology Biology Physics, 2021, 109, 603-613.

Pogue, B. W.; Zhang, R.; Cao, X.; Jia, J. M.; Petusseau, A.; Bruza, P.; Vinogradov, S. A. Review of in vivo optical molecular imaging and sensing from x-ray excitation J. Biomed. Optics, 2021, 26(1), Article number: 010902.


Ravotto, L.; Meloni, S. L.; Esipova, T. V.; Masunov, A. E.; Anna, J. M.; Vinogradov, S. A. Three-photon spectroscopy of porphyrins J. Phys. Chem. A, 2020, 124(52) 11038–11050.

Chin, K.; Cazorla-Bak, M. P.; Liu, E. E.; Nghiem, L.; Zhang, Y. L.; Yu, J. L.; Wilson, D. F.; Vinogradov, S. A.; Gilbert, R. E.; Connelly, K. A.; Evans, R. G.; Baker, A. J.; Mazer, C. D.; Hare, G. M. T. Renal microvascular oxygen tension during hyperoxia and acute hemodilution assessed by phosphorescence quenching and excitation with blue and red light. Can. J. Anesthesia D, 2020, 12.

Cao, X., Gunn, J. R., Allu, S. R., Bruza, P., Jiang, S., Vinogradov, S. A. Pogue, B. W.  Implantable sensor for local Cherenkov-excited luminescence imaging of tumor pO2 during radiotherapy. J. Biomed. Optics, 2020, 25(11),  Article number: 112704.

Ballester, M.; Ravotto, L.; Quirke, J. M. E.; de la Vega, R. L.; Shelnutt, J. A.; Cheprakov, A. V.; Vinogradov, S. A.;* Medforth, C. J.*  Protonation of Planar and Nonplanar Porphyrins: A Calorimetric and Computational Study. J. Phys. Chem. A, 2020, 124(43), 8994-9003.

Sencan, I.; Esipova, T.; Kilic, K.; Li, B. Q.; Desjardins, M.; Yaseen, M. A.; Wang, H.; Porter, J. E.; Kura, S.; Fu, B. Y.; Secomb, T. W.; Boas, D. A.; Vinogradov, S. A.; Devor, A.; Sakadzic, S.  Optical measurement of microvascular oxygenation and blood flow responses in awake mouse cortex during functional activation. J. Cereb. Blood Flow & Metab. 2020, Article number: 0271678X20928011.

Abrahamson, J. R.; Read, A.; Chin, K.; Mistry, N.; Joo, H.; Desjardins, J. F.; Liu, E.; Thai, K.; Wilson, D. F.; Vinogradov, S. A.; Maynes, J. T.; Gilbert, R. E.; Connelly, K. A.; Baker, A. J.; Mazer, C. D.; Hare, G. M. T.  Renal tissue pO2 sensing during acute hemodilution is dependent on the diluent. Am. J. Physiol., 2020, 318(4), R799-R812.

Ong, Y. H.; Miller, J.; Yuan, M.; Chandra, M.; El Khatib, M.; Vinogradov, S. A.; Putt, M. E.; Zhu, T. C.; Cengel, K. A.; Yodh, A. G.; Busch, T. M. Blood Flow Measurements Enable Optimization of Light Delivery for Personalized Photodynamic Therapy. Cancers, 2020, 12(6).

Bartosik, P.; Fitzgerald, J.; El Khatib, M.; Yaseen, M. A.; Vinogradov, S. A., Niedre, M.  Prospects for the Use of Upconverting Nanoparticles as a Contrast Agent for Enumeration of Circulating Cells in vivo  Intl. J. Nanomed.,  2020, 15, 1709-1719.

Christodoulou, C.; Spencer J. A.; Turcotte, R.; Kokkaliaris, K.D.; Panero, R.; Ramos, A.; Esipova, T. V.; Vinogradov, S. A.; Rudzinskas, S.; Zhang, Y.; Perkins, A.S.; Schroeder, T.; Lin, C. P.; Camargo, F.   Live-Animal Imaging of Native Hematopoietic Stem and Progenitor cells, Nature  2020, 578, 278-283.

Cao, X.; Rao Allu, S.; Jiang, S.; Jia, M.; Gunn, J. R.; Yao, C.; LaRochelle, E. P.; Shell, J. R.; Bruza, P.; Gladstone, D. J.; Jarvis, L. A.; Tian, J.; Vinogradov, S. A.;* Pogue, B. W.*  Tissue pO2 Distributions in Xenograft Tumors Dynamically Imaged by Cherenkov-Excited Phosphorescence during Fractionated Radiation TherapyNature Commun. 2020, 11,  Article number: 573.

Isokuortti, J.; Rao Allu, S.; Efimov, A.; Vuorimaa-Laukkanen, E.; Tkachenko, N. V.; Vinogradov, S. A.; Laaksonen, T.; Durandin, N. A. Endothermic and Exothermic Energy Transfer Made Equally Efficient for Triplet−Triplet Annihilation Upconversion,  J. Phys. Chem. Lett.  2020, 11, 318-324.

Plunkett, S.; El Khatib, M.; Sencan, I.; Porter, J.; Kumar, A. T. N.; Collins, J.; Sakadzic, S.; Vinogradov, S. A. In vivo deep-tissue microscopy with UCNP/Janus-dendrimers as imaging probes: resolution at depth and feasibility of ratiometric sensing,  Nanoscale   2020, 12, 2657-2672, DOI: 10.1039/c9nr07778b.


Sencan, I.; Esipova, T. V.; Yaseen, M. A.; Fu, B.; Boas, D. A.; Vinogradov, S. A.;* Shahidi, M.;* Sakadzic, S.*  Two-photon phosphorescence lifetime microscopy of retinal capillary plexus oxygenation in mice.  J. Biomed. Opt.  2019, 23 (12), 26501.

Villa, M.; Del Secco, B.; Ravotto, L.; Roy, M.; Rampazzo, E.; Zaccheroni, N.; Prodi, L.; Gingras, M.;* Vinogradov, S. A.;* Ceroni, P.*  Bright Phosphorescence of All-Organic Chromophores Confined within Water-Soluble Silica Nanoparticles. J. Phys. Chem. C  2019, 123 (49), 29884-29890.

Schilling, K.; El Khatib, M.; Plunkett, S.; Xue, J. J.; Xia, Y. N.; Vinogradov, S. A.;* Brown, E.;* Zhang, X. P.*  Electrospun Fiber Mesh for High-Resolution Measurements of Oxygen Tension in Cranial Bone Defect Repair.  ACS Appl. Mater. & Interf.  2019, 11 (37), 33548-33558.

Rytelewski, M.; Haryutyunan, K.; Nwajei, F.; Shanmugasundaram, M.; Wspanialy, P.; Zal, M. A.; Chen, C. H.; El Khatib, M.; Plunkett, S.; Vinogradov, S. A.; Konopleva, M.; Zal, T.  Merger of dynamic two-photon and phosphorescence lifetime microscopy reveals dependence of lymphocyte motility on oxygen in solid and hematological tumors.  J. Immunotherapy of Cancer  2019, 7.

Li, B. Q.; Esipova, T. V.; Sencan, I.; Kilic, K.; Fu, B. Y.; Desjardins, M.; Moeini, M.; Kura, S.; Yaseen, M. A.; Lesage, F.; Ostergaard, L.; Devor, A.; Boas, D. A.; Vinogradov, S. A.; Sakadzic, S.  More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction.  eLife  2019, 8.

Esipova, T. V.; Barrett, M. J. P.; Erlebach, E.; Masunov, A. E.; Weber, B.; Vinogradov, S. A.  Oxyphor 2P: A High-Performance Probe for Deep-Tissue Longitudinal Oxygen Imaging.  Cell Metabolism  2019, 29 (3), 736.

Canola, S.; Mardegan, L.; Bergamini, G.; Villa, M.; Acocella, A.; Zangoli, M.; Ravotto, L.; Vinogradov, S. A.;* Di Maria, F.; Ceroni, P.;* Negri, F.* One- and two-photon absorption properties of quadrupolar thiophene-based dyes with acceptors of varying strengths. Photochem. Photobiol. Sci.  2019, 18 (9), 2180-2190.

Del Secco, B.; Ravotto, L.; Esipova, T. V.; Vinogradov, S. A.;* Genovese, D.; Zaccheroni, N.; Rampazzo, E.;* Prodi, L.* Optimized synthesis of luminescent silica nanoparticles by a direct micelle-assisted method.  Photochem. Photobiol. Sci.  2019, 18 (9), 2142-2149.


Ahmed, S. R.; Jia, J. M.; Bruza, P.; Vinogradov, S.; Jiang, S. D.; Gladstone, D. J.; Jarvis, L. A.; Pogue, B. W.  Radiotherapy-induced Cherenkov luminescence imaging in a human body phantom. J. Biomed. Opt. 2018,  23 (3).

Friedman, E. S.; Bittinger, K.; Esipova, T. V.; Hou, L.; Chau, L.; Jiang, J.; Mesaros, C.; Lund, P. J.; Liang, X.; FitzGerald, G. A.; Goulian, M.; Lee, D.; Garcia, B. A.; Blair, I. A.; Vinogradov, S. A.;* Wu, G. D.*  Microbes vs chemistry in the origin of the anaerobic gut lumen.  PNAS   2018, 115 (16), 4170-4175.

Kisler, K.; Lazic, D.; Sweeney, M. D.; Plunkett, S.; El Khatib, M.; Vinogradov, S. A.; Boas, D. A.; Sakadzic, S.; Zlokovic, B. V.  In vivo imaging and analysis of cerebrovascular hemodynamic responses and tissue oxygenation in the mouse brain.  Nature Protocols  2018, 13 (6), 1377-1402.

Pogue, B. W.; Feng, J.; LaRochelle, E. P.; Bruza, P.; Lin, H.; Zhang, R.; Shell, J. R.; Dehghani, H.; Davis, S. C.; Vinogradov, S. A.; Gladstone, D. J.; Jarvis, L. A.  Maps of in vivo oxygen pressure with submillimetre resolution and nanomolar sensitivity enabled by Cherenkov-excited luminescence scanned imaging. Nature Biomed. Eng.  2018, 2 (4), 254-264.

Sencan, I.; Esipova, T. V.; Yaseen, M. A.; Fu, B. Y.; Boas, D. A.; Vinogradov, S. A.; Shahidi, M.; Sakadzic, S.  Two-photon phosphorescence lifetime microscopy of retinal capillary plexus oxygenation in mice.  J. Biomed. Opt.  2018, 23 (12).

Suilender, C. T.; Mark, A. E.; Clark, T. A.; Esipova, T. V.; Vinogradov, S. A.; Jones, T. A.; Dunn, A. K. Imaging of cortical oxygen tension and blood flow following targeted photothrombotic stroke.  Neurophotonics  2018, 5 (3).


Esipova, T. V.; Rivera-Jacquez, H. J.; Weber, B.; Masunov, A. E.; Vinogradov, S. A.  Stabilizing g-states in centrosymmetric tetrapyrroles: two-photon-absorbing porphyrins with bright phosphorescence.  J. Phys. Chem. A 2017, 121 (33), 6243-6255.

Ravotto, L.; Chen, Q.; Ma, Y.; Vinogradov, S. A.; Locritani, M.; Bergamini, G.; Negri, F.; Yu, Y.; Korgel, B. A.; Ceroni, P.  Bright Long-Lived Luminescence of Silicon Nanocrystals Sensitized by Two-Photon Absorbing Antenna.  Chem 2017, 2, 550–560.

Sencan, I.; Esipova, T.; Kilic, K.; Li, B.; Desjardins, M.; Yaseen, M. A.; Wang, H.; Jaswal, R.; Kura, S.; Fu, B.; Boas, D. A.; Devor, A.; Vinogradov, S. A.; Sakadzic, S.  Two-photon microscopy measurement of cortical functional activation in awake mice. J. Cereb. Blood Flow and Metab. 2017, 37, 15.


Alemayehu, A. B.; Day, N. U.; Mani, T.; Rudine, A. B.; Thomas, K. E.; Gederaas, O. A.; Vinogradov, S. A.;* Wamser, C. C.;* Ghosh, A.*  Gold Tris(carboxyphenyl)corroles as Multifunctional Materials: Room Temperature Near-IR Phosphorescence and Applications to Photodynamic Therapy and Dye-Sensitized Solar Cells. ACS Applied Materials & Interfaces 2016, 8 (29), 18935-18942.

Bruza, P.; Lin, H. Y.; Vinogradov, S. A.; Jarvis, L. A.; Gladstone, D. J.; Pogue, B. W.  Light sheet luminescence imaging with Cherenkov excitation in thick scattering media. Optics Letters 2016, 41 (13), 2986-2989.

Esipova, T. V.; Rivera-Jacquez, H. J.; Weber, B.; Masunov, A. E.; Vinogradov, S. A.  Two-photon absorbing phosphorescent metalloporphyrins: effects of π-extension and peripheral substitution. J. Am. Chem. Soc. 2016, 138 (48), 15648-15662.

Lin, H. Y.; Zhang, R. X.; Gunn, J. R.; Esipova, T. V.; Vinogradov, S.; Gladstone, D. J.; Jarvis, L. A.; Pogue, B. W.  Comparison of Cherenkov excited fluorescence and phosphorescence molecular sensing from tissue with external beam irradiation.  Physics in Medicine and Biology 2016, 61 (10), 3955-3968.

Uhlirova, H.; Kilic, K.; Tian, P. F.; Sakadzic, S.; Gagnon, L.; Thunemann, M.; Desjardins, M.; Saisan, P. A.; Nizar, K.; Yaseen, M. A.; Hagler, D. J.; Vandenberghe, M.; Djurovic, S.; Andreassen, O. A.; Silva, G. A.; Masliah, E.; Kleinfeld, D.; Vinogradov, S.; Buxton, R. B.; Einevoll, G. T.; Boas, D. A.; Dale, A. M.; Devor, A.  The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements. Philosophical Transactions of the Royal Society B-Biological Sciences 2016, 371 (1705).

Xiao, Q.; Rubien, J. D.; Wang, Z. C.; Reed, E. H.; Hammer, D. A.; Sahoo, D.; Heiney, P. A.; Yadavalli, S. S.; Goulian, M.; Wilner, S. E.; Baumgart, T.; Vinogradov, S. A.; Klein, M. L.; Percec, V.  Self-Sorting and Coassembly of Fluorinated, Hydrogenated, and Hybrid Janus Dendrimers into Dendrimersomes.  J. Am. Chem. Soc. 2016, 138 (38), 12655-12663.

Sakadžić, S.; Yaseen, M. A.; Jaswal, R.; Rousakis, E.; Dale, A. M.; Buxton, R. B.; Vinogradov, S. A.; Boas, D. A.; Devor, A.  Two-photon microscopy measurement of cerebral metabolic rate of oxygen using periarteriolar oxygen concentration gradients.  Neurophotonics 2106, 3 (4), 045005.


Cerniglia, G. J.; Dey, S.; Gallagher-Colombo, S. M.; Daurio, N. A.; Tuttle, S.; Busch, T. M.; Lin, A.; Sun, R.; Esipova, T. V.; Vinogradov, S. A.; Denko, N.; Koumenis, C.; Maity, A.  The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1 alpha Phosphorylation. Molecular Cancer Therapeutics 2015, 14 (8), 1928-1938.

Falk, S. J.; Guo, L. Y.; Sekulic, N.; Smoak, E. M.; Mani, T.; Logsdon, G. A.; Gupta, K.; Jansen, L. E. T.; Van Duyne, G. D.; Vinogradov, S. A.; Lampson, M. A.; Black, B. E.  CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere. Science 2015, 348 (6235), 699-703.

Gallagher-Colombo, S. M.; Miller, J.; Cengel, K. A.; Putt, M. E.; Vinogradov, S. A.; Busch, T. M.  Erlotinib Pretreatment Improves Photodynamic Therapy of Non-Small Cell Lung Carcinoma Xenografts via Multiple Mechanisms. Cancer Research 2015, 75 (15), 3118-3126.

Zhang, R.; Dsouza, A.; Gunn, J.; Esipova, T.; Vinogradov, S.; Glaser, A.; Jarvis, L.; Gladstone, D.; Pogue, B. Cherenkov-Excited Luminescence Scanned Imaging (CELSI) for High-Resolution Deep-Tissue in Vivo Optical Molecular Imaging with Limited Radiation Dose. Medical Physics 2015, 42 (6), 3713-3714.

Zhang, R. X.; D'Souza, A. V.; Gunn, J. R.; Esipova, T. V.; Vinogradov, S. A.; Glaser, A. K.; Jarvis, L. A.; Gladstone, D. J.; Pogue, B. W.  Cherenkov-excited luminescence scanned imaging. Optics Letters 2015, 40 (5), 827-830.


Esipova, T. V.; Vinogradov, S. A. Synthesis of Phosphorescent Asymmetrically π-Extended Porphyrins for Two-Photon Applications.  J. Org. Chem.  2014, 79 (18), 8812-8825.

Holt, R. W.; Zhang, R. X.; Esipova, T. V.; Vinogradov, S. A.; Glaser, A. K.; Gladstone, D. J.; Pogue, B. W.  Cherenkov excited phosphorescence-based pO2 estimation during multi-beam radiation therapy: phantom and simulation studies. Physics in Medicine and Biology  2014, 59 (18), 5317-5328.

Roussakis, E.; Spencer, J. A.; Lin, C.; Vinogradov, S. A. Two-photon antenna-core oxygen probe with enhanced performance.  Anal. Chem.  2014, 86, 5937-5945.

Spencer, J. A.; Ferraro, F.; Roussakis, E.; Klein, A.; Wu, J. W.; Runnels, J. M.; Zaher, W.; Mortensen, L. J.; Alt, C.; Turcotte, R.; Yusuf, R.; Cote, D.; Vinogradov, S. A.; Scadden, D. T.; Lin, C. P.  Direct measurement of local oxygen concentration in the bone marrow of live animals. Nature   2014,  508 (7495), 269.

White, S. M.; Pittman, C. R.; Hingorani, R.; Arora, R.; Esipova, T. V.; Vinogradov, S. A.; Hughes, C. C. W.; Choi, B.; George, S. C. Implanted Cell-Dense Prevascularized Tissues Develop Functional Vasculature That Supports Reoxygenation After Thrombosis. Tissue Engineering Part A  2014, 20 (17-18), 2316-2328.

Wilson, D. F.;* Vinogradov, S. A. Mitochondrial cytochrome c oxidase: mechanism of action and role in regulating oxidative phosphorylation.  J. Appl. Physiol.  2014, 117 (12), 1431-1439.

Zhang, R.; Holt, R.; Esipova, T.; Vinogradov, S.; Gladstone, D.; Pogue, B. Cherenkov-Excited Phosphorescence Oxygen (CEPhOx) Imaging During Multi-Beam Radiation Therapy.  Medical Physics  2014, 41 (6), 554-555.


Albenberg, L.; Judge, C. P.; Esipova, T. V.; Sinha, R.; Bailey, A. G.; Bittinger, K.; Grunberg, S.; Chen, J.; Bhopale, V. M.; Baldassano, R.; Lewis, J. D.; Li, H. Z.; Thom, S. R.; Bushman, F. D.; Vinogradov, S.A;* Wu, G. D.*  Biological Oximetry Using Phosphorescence Quenching Reveals a Dynamic Oxygen Equilibrium Maintained Between the Gut Microbiota and the Host. Gastroenterology 2013, 144 (5), S156-S157.

Devor, A.; Bandettini, P. A.; Boas, D. A.; Bower, J. M.; Buxton, R. B.; Cohen, L. B.; Dale, A. M.; Einevoll, G. T.; Fox, P. T.; Franceschini, M. A.; Friston, K. J.; Fujimoto, J. G.; Geyer, M. A.; Greenberg, J. H.; Halgren, E.; Hamalainen, M. S.; Helmchen, F.; Hyman, B. T.; Jasanoff, A.; Jernigan, T. L.; Judd, L. L.; Kim, S. G.; Kleinfeld, D.; Kopell, N. J.; Kutas, M.; Kwong, K. K.; Larkum, M. E.; Lo, E. H.; Magistretti, P. J.; Mandeville, J. B.; Masliah, E.; Mitra, P. P.; Mobley, W. C.; Moskowitz, M. A.; Nimmerjahn, A.; Reynolds, J. H.; Rosen, B. R.; Salzberg, B. M.; Schaffer, C. B.; Silva, G. A.; So, P. T. C.; Spitzer, N. C.; Toote, R. B.; Van Essen, D. C.; Vanduffe, W.; Vinogradov, S. A.; Wald, L. L.; Wang, L. V.; Weber, B.; Yodh, A. G.  The Challenge of Connecting the Dots in the BRAIN.  Neuron  2013, 80 (2), 270-274.

Kazmi, S. M. S.; Salvaggio, A. J.; Estrada, A. D.; Hemati, M. A.; Shaydyuk, N. K.; Roussakis, E.; Jones, T. A.; Vinogradov, S. A.; Dunn, A. K. Three-dimensional mapping of oxygen tension in cortical arterioles before and after occlusion.  Biomed. Opt. Express  2013, 4 (7), 1061-1073.

Mani, T.; Vinogradov, S. A. Magnetic Field Effects on Triplet-Triplet Annihilation in Solutions: Modulation of Visible/NIR Luminescence.  J. Phys. Chem. Lett.  2013, 4 (17), 2799-2804.

Yu, J.; Ramadeen, A.; Tsui, A. K. Y.; Hu, X.; Zou, L.; Wilson, D. F.; Esipova, T. V.; Vinogradov, S. A.; Leong-Poi, H.; Zamiri, N.; Mazer, C. D.; Dorian, P.; Hare, G. M. T.  Quantitative assessment of brain microvascular and tissue oxygenation during cardiac arrest and resuscitation in pigs.  Anaesthesia  2013, 68 (7), 723-735.

Zhang, R. X.; Davis, S. C.; Demers, J. L. H.; Glaser, A. K.; Gladstone, D. J.; Esipova, T. V.; Vinogradov, S. A.; Pogue, B. W.  Oxygen tomography by Cerenkov-excited phosphorescence during external beam irradiation.  J. Biomed. Opt.  2013, 18 (5).


Chen, P.; Finikova, O. S.; Ou, Z. P.; Vinogradov, S. A.;* Kadish, K. M.*  Electrochemistry of Platinum(II) Porphyrins: Effect of Substituents and π-Extension on Redox Potentials and Site of Electron Transfer.  Inorg. Chem.  2012, 51 (11), 6200-6210.

Devor, A.; Sakadzic, S.; Srinivasan, V. J.; Ayaseen, M.; Nizar, K.; Saisan, P. A.; Tian, P. F.; Dale, A. M.; Vinogradov, S. A.; Franceschini, M. A.; Boas, D. A.  Frontiers in optical imaging of cerebral blood flow and metabolism.  J. Cereb. Blood Flow and Metab.  2012, 32 (7), 1259-1276.

Esipova, T. V.; Ye, X. C.; Collins, J. E.; Sakadzic, S.; Mandeville, E. T.; Murray, C. B.; Vinogradov, S. A.  Dendritic upconverting nanoparticles enable in vivo multiphoton microscopy with low-power continuous wave sources.  PNAS.  2012, 109 (51), 20826-20831.

Lichtenstein, B. R.; Farid, T. A.; Kodali, G.; Solomon, L. A.; Anderson, J. L. R.; Sheehan, M. M.; Ennist, N. M.; Fry, B. A.; Chobot, S. E.; Bialas, C.; Mancini, J. A.; Armstrong, C. T.; Zhao, Z. Y.; Esipova, T. V.; Snell, D.; Vinogradov, S. A.; Discher, B. M.; Moser, C. C.; Dutton, P. L.  Engineering oxidoreductases: maquette proteins designed from scratch.  Biochem. Soc. Trans.  2012, 40, 561-566.

Mani, T.; Niedzwiedzki, D. M.; Vinogradov, S. A.  Generation of Phosphorescent Triplet States via Photoinduced Electron Transfer: Energy and Electron Transfer Dynamics in Pt Porphyrin-Rhodamine B Dyads.  J. Phys. Chem. A.  2012, 116, 3598-3610.

Mani, T.; Tanabe, M.; Yamauchi, S.; Tkachenko, N. V.; Vinogradov, S. A.  Modulation of Visible Room Temperature Phosphorescence by Weak Magnetic Fields.  J. Phys. Chem. Lett. 2012, 3 (21), 3115-3119.

Mesquita, R. C.; Han, S. W.; Miller, J.; Schenkel, S. S.; Pole, A.; Esipova, T. V.; Vinogradov, S. A.; Putt, M. E.; Yodh, A. G.; Busch, T. M.  Tumor Blood Flow Differs between Mouse Strains: Consequences for Vasoresponse to Photodynamic Therapy. PloS One  2012, 7 (5).

Vinogradov, S. A.; Wilson, D. F. Porphyrin-dendrimers as biological oxygen sensors. In Designing Dendrimers, Capagna, S.; Ceroni, P., Eds. Wiley: New York, 2012.

Wilson, D. F.;* Harrison, D. K.; Vinogradov, S. A.  Oxygen, pH, and mitochondrial oxidative phosphorylation.  J. Appl. Physiol.  2012, 113 (12), 1838-1845.

Zhang, R.; Kanick, S.; Vinogradov, S. A.; Esipova, T.; Pogue, B. W.  External Beam Radiation Cherenkov Emission in Tissue Used for Tissue Oxygen Sensing.  Medical Physics  2012, 39 (6), 3646-3646.

Zhang, R. X.; Glaser, A.; Esipova, T. V.; Kanick, S. C.; Davis, S. C.; Vinogradov, S. A.; Gladstone, D.; Pogue, B. W.  Cerenkov radiation emission and excited luminescence (CREL) sensitivity during external beam radiation therapy: Monte Carlo and tissue oxygenation phantom studies.  Biomed. Opt. Express 2012, 3 (10), 2381-2394.


Ceroni, P.; Lebedev, A. Y.; Marchi, E.; Yuan, M.; Esipova, T. V.; Bergamini, G.; Wilson, D. F.; Busch, T. M.; Vinogradov, S. A.  Evaluation of phototoxicity of dendritic porphyrin-based phosphorescent oxygen probes: an in vitro study.  Photochem. Photobiol. Sci.  2011, 10 (6), 1056-1065.

Devor, A.; Sakadzic, S.; Saisan, P. A.; Yaseen, M. A.; Roussakis, E.; Srinivasan, V. J.; Vinogradov, S. A.; Rosen, B. R.; Buxton, R. B.; Dale, A. M.; Boas, D. A.  "Overshoot" of O2 Is Required to Maintain Baseline Tissue Oxygenation at Locations Distal to Blood Vessels.  J. Neurosci.  2011, 31 (38), 13676-13681.

Esipova, T. V.; Karagodov, A.; Miller, J.; Wilson, D. F.; Busch, T. M.; Vinogradov, S. A.  Two new "protected" oxyphors for biological oximetry: properties and application in tumor imaging.  Anal. Chem. 2011, 83 (22), 8756-8765.

Hiesinger, W.; Vinogradov, S. A.; Atluri, P.; Fitzpatrick, J. R.; Frederick, J. R.; Levit, R. D.; McCormick, R. C.; Muenzer, J. R.; Yang, E. C.; Marotta, N. A.; MacArthur, J. W.; Wilson, D. F.; Woo, Y. J.  Oxygen-dependent quenching of phosphorescence used to characterize improved myocardial oxygenation resulting from vasculogenic cytokine therapy.  J. Appl. Physiol.  2011, 110 (5), 1460-1465.

Lecoq, J.; Parpaleix, A.; Roussakis, E.; Ducros, M.; Houssen, Y. G.; Vinogradov, S. A.;* Charpak, S.* Simultaneous two-photon imaging of oxygen and blood flow in deep cerebral vessels.  Nature Medicine. 2011, 17 (7), 893-898.

Pedersen, B. W.; Sinks, L. E.; Breitenbach, T.; Schack, N. B.; Vinogradov, S. A.; Ogilby, P. R.  Single cell responses to spatially controlled photosensitized production of extracellular singlet oxygen.  Photochem. Photobiol. 2011, 87 (5), 1077-1091.

Wilson, D. F.;* Finikova, O. S.; Lebedev, A. Y.; Apreleva, S.; Pastuszko, A.; Lee, W. M. F.; Vinogradov, S. A. Measuring oxygen in living tissue: intravascular, interstitial and "tissue" oxygen measurements. In Oxygen Transport to Tissue XXXII,  Adv. Exp. Med. Biol., 2011, 701, 53-59.


Bdeir, K.; Higazi, A. A. R.; Kulikovskaya, I.; Christofidou-Solomidou, M.; Vinogradov, S. A.; Aliens, T. C.; Idell, S.; Linzmeier, R.; Ganz, T.; Cines, D. B.  Neutrophil alpha-Defensins Cause Lung Injury by Disrupting the Capillary-Epithelial Barrier.  Amer. J. Resp. Crit. Care Med. 2010, 181 (9), 935-946.

Doliba, N. M.; Qin, W.; Vinogradov, S. A.; Wilson, D. F.; Matschinsky, F. M.  Palmitic acid acutely inhibits acetylcholine- but not GLP-1-stimulated insulin secretion in mouse pancreatic islets.  Amer. J. Physiol. Endocrinology and Metabolism  2010, 299 (3), E475-E485.

Filatov, M. A.; Lebedev, A. Y.; Mukhin, S. N.; Vinogradov, S. A.;* Cheprakov, A. V.*  π-Extended dipyrrins capable of highly fluorogenic complexation with metal ions.  J. Am. Chem. Soc. 2010, 132 (28), 9552-9554.

Leiding, T.; Martinsson, J.; Vinogradov, S.; Hagerhall, C.; Arskold, S. P.   A systematic approach to membrane-protein reconstitution in liposomes, applied to the M2 protein of Influenza virus A.  Biochimica Et Biophysica Acta-Bioenergetics 2010, 1797, 22-22.

Sakadzic, S.; Roussakis, E.; Yaseen, M. A.; Mandeville, E. T.; Srinivasan, V. J.; Arai, K.; Ruvinskaya, S.; Devor, A.; Lo, E. H.; Vinogradov, S. A.;* Boas, D. A.*  Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue.  Nature Methods  2010, 7 (9), 755-759.

Sinks, L. E.; Robbins, G. P.; Roussakis, E.; Troxler, T.; Hammer, D. A.; Vinogradov, S. A.  Two-photon microscopy of oxygen: polymersomes as probe carrier vehicles. J. Phys. Chem. B  2010, 114 (45), 14373-14382.

Thyagarajan, S.; Leiding, T.; Arskold, S. P.; Cheprakov, A. V.; Vinogradov, S. A.  Highly non-planar dendritic porphyrin for pH sensing: observation of  porphyrin monocation.  Inorg. Chem. 2010, 49 (21), 9909-9920.


Lebedev, A. Y.; Cheprakov, A. V.; Sakadzic, S.; Boas, D. A.; Wilson, D. F.; Vinogradov, S. A.  Dendritic phosphorescent probes for oxygen imaging in biological systems.  ACS Appl. Materials & Interfaces  2009, 1 (6), 1292-1304.

Leiding, T.; Gorecki, K.; Kjellman, T.; Vinogradov, S. A.; Hagerhall, C.; Arskold, S. P.  Precise detection of pH inside large unilamellar vesicles using membrane-impermeable dendritic porphyrin-based nanoprobes.  Anal. Biochem.  2009, 388 (2), 296-305.

Sakadzic, S.; Yuan, S.; Dilekoz, E.; Ruvinskaya, S.; Vinogradov, S. A.; Ayata, C.; Boas, D. A.  Simultaneous imaging of cerebral partial pressure of oxygen and blood flow during functional activation and cortical spreading depression.  Applied Optics  2009, 48 (10), D169-D177.

Yaseen, M.; Srinivasan, V.; Sakadzic, S.; Vinogradov, S.; Ayata, C.; Boas, D.  Monitoring oxygen partial pressure in cerebral microvasculature with high spatial resolution using phosphorescence lifetime imaging.  J. Cereb. Blood Flow and Metabolism  2009, 29, S382-S382.

Yaseen, M. A.; Srinivasan, V. J.; Sakadzic, S.; Wu, W.; Ruvinskaya, S.; Vinogradov, S. A.; Boas, D. A.  Optical monitoring of oxygen tension in cortical microvessels with confocal microscopy.  Opt. Express  2009, 17 (25), 22341-22350.


Apreleva, S. V.; Vinogradov, S. A.  Influence of optical heterogeneities on reconstruction of spatial phosphorescence lifetime distributions. Optics Letters  2008, 33 (8), 782-784.

Filatov, M. A.; Lebedev, A. Y.; Vinogradov, S. A.;* Cheprakov, A. V.*  Synthesis of 5,15-diaryltetrabenzoporphyrins. J. Org. Chem.  2008, 73 (11), 4175-4185.

Finikova, O. S.; Chen, P.; Ou, Z.; Kadish, K. M.; Vinogradov, S. A.  Dynamic quenching of porphyrin triplet states by two-photon absorbing dyes: Towards two-photon-enhanced oxygen nanosensors.  J. Photochem. Photobiol.  A 2008, 198 (1), 75-84.

Finikova, O. S.; Lebedev, A. Y.; Aprelev, A.; Troxler, T.; Gao, F.; Garnacho, C.; Muro, S.; Hochstrasser, R. M.; Vinogradov, S. A.  Oxygen microscopy by two-photon-excited phosphorescence.  ChemPhysChem  2008, 9 (12), 1673-1679.

Lebedev, A. Y.; Filatov, M. A.; Cheprakov, A. V.;* Vinogradov, S. A.*  Effects of structural deformations on optical properties of tetrabenzoporphyrins: Free-bases and Pd complexes. J. Phys. Chem. A  2008, 112 (33), 7723-7733.

Lebedev, A. Y.; Troxler, T.; Vinogradov, S. A.  Design of metalloporphyrin-based dendritic nanoprobes for two-photon microscopy of oxygen.  J. Porph. Phthalocyan.  2008,12(12), 1261-1269.


Finikova, O. S.; Troxler, T.; Senes, A.; DeGrado, W. F.; Hochstrasser, R. M.; Vinogradov, S. A.  Energy and electron transfer in enhanced two-photon-absorbing systems with triplet cores. J. Phys. Chem. A 2007, 111 (30), 6977-6990.

Kaucher, M. S.; Peterca, M.; Dulcey, A. E.; Kim, A. J.; Vinogradov, S. A.; Hammer, D. A.; Heiney, P. A.; Percec, V.  Selective transport of water mediated by porous dendritic dipeptides. J. Am. Chem. Soc. 2007, 129 (38), 11698.


Apreleva, S. V.; Wilson, D. E.; Vinogradov, S. A.  Feasibility of diffuse optical imaging with long-lived luminescent probes.  Optics Letters2006, 31(8), 1082-1084.

Apreleva, S. V.; Wilson, D. F.; Vinogradov, S. A.  Tomographic imaging of oxygen by phosphorescence lifetime.  Applied Optics, 2006, 45(33), 8547-8559.

Dichtel, W. R.; Baek, K. Y.; Frechet, J. M. J.; Rietveld, I. B.; Vinogradov, S. A.  Amphiphilic diblock star polymer catalysts via atom transfer radical polymerization.  J. Polymer Sci. A-Polymer Chem. 2006, 44 (17), 4939-4951.

Ranji, M.; Laggard, D. L.; Apreleva, S. V.; Vinogradov, S. A.; Chance, B.  Simultaneous fluorometry and phosphorometry of Langendorff perfused rat heart: ex vivo animal studies.  Optics Letters 2006, 31(20), 2995-2997.

Wilson, D. F.; Lee, W. M. F.; Makonnen, S.; Finikova, O.; Apreleva, S.; Vinogradov, S. A.  Oxygen pressures in the interstitial space and their relationship to those in the blood plasma in resting skeletal muscle.  J. Appl. Physiol. 2006, 101(6), 1648-1656.


Brinas, R. P.; Troxler, T.; Hochstrasser, R. M.; Vinogradov, S. A.  Phosphorescent oxygen sensor with dendritic protection and two-photon absorbing antenna.  J. Am. Chem. Soc.  2005, 127 (33), 11851-11862.

Finikova, O. S.; Aleshchenkov, S. E.; Brinas, R. P.; Cheprakov, A. V.; Carroll, P. J.; Vinogradov, S. A.  Synthesis of symmetrical tetraaryltetranaphtho[2,3]porphyrins.  J. Org. Chem.  2005, 70 (12), 4617-4628.

Finikova, O. S.; Cheprakov, A. V.; Vinogradov, S. A.  Synthesis and luminescence of soluble meso-unsubstituted tetrabenzo- and tetranaphtho[2,3]porphyrins.  J. Org. Chem.  2005, 70 (23), 9562-9572.

Mei, E. W.; Gao, F.; Vinogradov, S.; Vanderkooi, J. M.; Hochstrasser, R. M.  Phosphorescence of individual horseradish peroxidase proteins having a modified heme group.  Chem. Phys. Lett.  2005, 401 (1-3), 30-34.

Vacarezza, M. N.; Vinogradov, S. A.; Antoni, D.; Bennett, J.; Laties, A.; Wilson, D. F. Oxygen measurements in the retina using phosphorescence lifetime imaging.  Investigative Ophthalmology & Visual Science 2005, 46.

Vinogradov, S. A.  Arylamide dendrimers with flexible linkers via haloacyl halide method. Organic Lett.  2005, 7 (9), 1761-1764.

Wilson, D. F.; Vinogradov, S. A.; Grosul, P.; Vaccarezza, M. N.; Kuroki, A.; Bennett, J.  Oxygen distribution and vascular injury in the mouse eye measured by phosphorescence-lifetime imaging. Applied Optics 2005, 44 (25), 5239-5248.

Ziemer, L. S.; Lee, W. M. F.; Vinogradov, S. A.; Sehgal, C.; Wilson, D. F.  Oxygen distribution in murine tumors: characterization using oxygen-dependent quenching of phosphorescence. J. Appl. Physiol. 2005, 98 (4), 1503-1510.


Finikova, O. S.; Cheprakov, A. V.; Beletskaya, I. P.; Carroll, P. J.; Vinogradov, S. A.  Novel versatile synthesis of substituted tetrabenzoporphyrins.  J. Org. Chem. 2004, 69 (2), 522-535.

Nibbs, J.; Vinogradov, S. A.; Vanderkooi, J. M.; Zelent, B.  Flexibility in proteins: Tuning the sensitivity to O-2 diffusion by varying the lifetime of a phosphorescent sensor in horseradish peroxidase. Photochem. Photobiol.  2004, 80 (1), 36-40.

Percec, V.;* Dulcey, A. E.; Balagurusamy, V. S. K.; Miura, Y.; Smidrkal, J.; Peterca, M.; Nummelin, S.; Edlund, U.; Hudson, S. D.; Heiney, P. A.; Hu, D. A.; Magonov, S. N.; Vinogradov, S. A.  Self-assembly of amphiphilic dendritic dipeptides into helical pores.  Nature 2004, 430 (7001), 764-768.

Soloviev, V. Y.; Wilson, D. F.; Vinogradov, S. A.  Phosphorescence lifetime imaging in turbid media: the inverse problem and experimental image reconstruction.  Applied Optics  2004, 43 (3), 564-574.

Sund, N. J.; Vinogradov, S. A.; Tolentino, M. J.; Bennett, J.; Wilson, D. F.  Retinal oxygen imaging in mice by phosphorescence lifetime.  Investigative Ophthalmology & Visual Science 2004, 45, U733-U733.


Finikova, O. S.; Cheprakov, A. V.; Carroll, P. J.; Vinogradov, S. A.  Novel route to functionalized tetraaryltetra[2,3]naphthaloporphyrins via oxidative aromatization.  J. Org. Chem.  2003, 68 (19), 7517-7520.

Finikova, O. S.; Galkin, A. S.; Rozhkov, V. V.; Cordero, M. C.; Hagerhall, C.; Vinogradov, S. A.  Porphyrin and tetrabenzoporphyrin dendrimers: Tunable membrane- impermeable fluorescent pH nanosensors.  J. Am. Chem. Soc.  2003, 125 (16), 4882-4893.

Khajehpour, M.; Rietveld, I.; Vinogradov, S.; Prabhu, N. V.; Sharp, K. A.; Vanderkooi, J. M.  Accessibility of oxygen with respect to the heme pocket in horseradish peroxidase.  Proteins-Structure Function and Genetics 2003, 53 (3), 656-666.

Mei, E. W.; Vinogradov, S.A.; Hochstrasser, R. M.  Direct observation of triplet state emission of single molecules: Single molecule phosphorescence quenching of metalloporphyrin and organometallic complexes by molecular oxygen and their quenching rate distributions.  J. Am. Chem. Soc.  2003, 125 (43), 13198-13204.

Rietveld, I. B.; Kim, E.; Vinogradov, S. A.  Dendrimers with tetrabenzoporphyrin cores: near infrared phosphors for in vivo oxygen imaging.  Tetrahedron 2003, 59 (22), 3821-3831.

Rogers, J. E.; Nguyen, K. A.; Hufnagle, D. C.; McLean, D. G.; Su, W. J.; Gossett, K. M.; Burke, A. R.; Vinogradov, S. A.; Pachter, R.; Fleitz, P. A.  Observation and interpretation of annulated porphyrins: Studies on the photophysical properties of meso-tetraphenylmetalloporphyrins.  J. Phys. Chem. A 2003, 107 (51), 11331-11339.

Rozhkov, V. V.; Khajehpour, M.; Vinogradov, S. A.  Luminescent Zn and Pd tetranaphthaloporphyrins. Inorg. Chem. 2003, 42 (14), 4253-4255.

Soloviev, V.; Wilson, D.; Vinogradov, S.A.  Phosphorescence lifetime imaging in turbid media: the forward problem. Applied Optics 2003, 42 (1), 113-123.


Dunphy, I.; Vinogradov, S. A.; Wilson, D. F.  Oxyphor R2 and G2: phosphors for measuring oxygen by oxygen- dependent quenching of phosphorescence. Anal. Biochem.  2002, 310 (2), 191-198.

Finikova, O. S.; Cheprakov, A. V.; Carroll, P. J.; Dalosto, S.; Vinogradov, S. A.  Influence of nonplanarity and extended conjugation on porphyrin basicity. Inorg. Chem.  2002, 41 (26), 6944-6946.

Rozhkov, V.; Wilson, D.; Vinogradov, S.A.  Phosphorescent Pd porphyrin-dendrimers: Tuning core accessibility by varying the hydrophobicity of the dendritic matrix. Macromolecules  2002, 35 (6), 1991-1993.

Vinogradov, S. A.; Fernandez-Seara, M. A.; Dupan, B. W.; Wilson, D. F.  A method for measuring oxygen distributions in tissue using frequency domain phosphorometry. Comparative Biochemistry and Physiology a-Molecular and Integrative Physiology 2002, 132 (1), 147-152.

Wilson, D. F.; Vinogradov, S. A.; Dugan, B. W.; Biruski, D.; Waldron, L.; Evans, S. A. Measurement of tumor oxygenation using new frequency domain phosphorometers. Comparative Biochemistry and Physiology a-Molecular and Integrative Physiology 2002, 132 (1), 153-159.


Finikova, O.; Cheprakov, A.; Beletskaya, I.; Vinogradov, S.A.  An expedient synthesis of substituted tetraaryltetrabenzoporphyrins.  Chem. Commun. 2001,  (3), 261-262.

Friedberg, J. S.; Skema, C.; Baum, E. D.; Burdick, J.; Vinogradov, S. A.; Wilson, D. F.; Horan, A. D.; Nachamkin, I.  In vitro effects of photodynamic therapy on Aspergillus fumigatus. J. Antimicrobal Chemotherapy 2001, 48, 105-107.

Vinogradov, S. A.;* Fernandez-Seara, M. A.; Dugan, B. W.; Wilson, D. F.  Frequency domain instrument for measuring phosphorescence lifetime distributions in heterogeneous samples. Rev. Sci. Instrum. 2001, 72 (8), 3396-3406.


Vinogradov, S. A.; Wilson, D. F.  Electrostatic core shielding in dendritic polyglutamic porphyrins. Chem. Eur. J. 2000, 6 (13), 2456-2461.

Vinogradov, S.A.; Wilson, D. F.  Recursive maximum entropy algorithm and its application to the luminescence lifetime distribution recovery. Appl. Spectrosc. 2000, 54 (6), 849-855.